Papers & Reviews
Ishii R, Yanagisawa H*, Sada A*: Defining compartmentalized stem cell populations with distinct cell division dynamics in the ocular surface epithelium.
Oinam L, Changarathil G, Raja E, Yen Ngo YX, Tateno H, Sada A*, Yanagisawa H: Glycome profiling by lectin microarray reveals dynamic glycan alterations during epidermal stem cell aging.
* Corresponding author
Kang S, Long K, Wang S, Sada A, and Tumbar T: Histone H3 K4/9/27 trimethylation levels affect wound healing and stem cell dynamics in adult skin.
Changarathil G, Ramirez K, Isoda H, Sada A*, Yanagisawa H: Wild-type and SAMP8 mice show age-dependent changes in distinct stem cell compartments of the interfollicular epidermis.
* Corresponding author
Oinam L, Changarathil G, Ngo YX, Yanagisawa H, Sada A*: Epidermal stem cell lineages.
* Corresponding author
Advances in Stem Cells and their Niches, 2019 (A book chapter) [Full Text]
Tsunezumi J, Sugiura H, Oinam L, Ali A, Thang BQ, Sada A, Yamashiro Y, Kuro-O M, and Yanagisawa H: Fibulin-7, a heparin binding matricellular protein, promotes renal tubular calcification in mice.
Sada A, Jain P, Wang S, Leung E, Tumbar T: Slc1a3-CreER as a targeting tool for the K6+ epithelial stem cell niche and its precursors during mouse hair follicle cycle.
Sada A, Jacob F, Leung E, Wang S, White BS, Shalloway D and Tumbar T: Defining the cellular lineage hierarchy in the interfollicular epidermis of adult skin.
Zhou Z, Shirakawa T, Ohbo K, Sada A, Wu Q, Hasegawa K, Saba R and Saga Y: RNA binding protein Nanos2 organizes post-transcriptional buffering system to retain primitive state of mouse spermatogonial stem cells.
Lee SE, Sada A, Zhang M, McDermitt DJ, Lu SY, Kemphues KJ and Tumbar T: High Runx1 levels promote a reversible, more-differentiated cell state in hair-follicle stem cells during quiescence.
Sada A and Tumbar T: New insights into mechanisms of stem cell daughter fate determination in regenerative tissues.
Sada A, Hasegawa K, Pin PH and Saga Y: NANOS2 acts downstream of glial cell line-derived neurotrophic factor signaling to suppress differentiation of spermatogonial stem cells.
Suzuki H, Saba R, Sada A and Saga Y: The Nanos3-3'UTR is required for germ cell specific NANOS3 expression in mouse embryos.
Suzuki H, Sada A, Yoshida S and Saga Y: The heterogeneity of spermatogonia is revealed by their topology and expression of marker proteins including the germ cell-specific proteins Nanos2 and Nanos3.
Sada A, Suzuki A, Suzuki H and Saga Y: The RNA-binding protein NANOS2 is required to maintain murine spermatogonial stem cells.
Yamasaki H, Sada A, Iwata T, Niwa T, Tomizawa M, Xanthopoulos KG, Koike T and Shiojiri N: Suppression of C/EBPalpha expression in periportal hepatoblasts may stimulate biliary cell differentiation through increased Hnf6 and Hnf1b expression.
INVITED TALKS (international meeting)
Sada A: Maintenance of heterogeneous epidermal stem cell populations by the distinct niche, Japan-Singapore International Skin Conference 2019, Singapore, April 10-12, 2019
Sada A: Defining the stem cell lineages in adult skin epidermis: CDB Symposium, Kobe, Japan, March 26-28, 2018
Sada A: Stem Cell Lineages of the Interfollicular Epidermis. Gordon Research Conference, Tissue Niches & Resident Stem Cells in Adult Epithelia, Hong Kong, China, August 7-12, 2016
Japan Agency for Medical Research and Development (AMED) /AMED-PRIME (JP20gm6110016), Elucidating the cellular and molecular mechanisms of epithelial stem cell aging, 52,000,000 yen, 2018 – 2021
Grant-in-Aid for Scientific Research (B) (20H03266). Molecular and cellular mechanisms to define the compartmentalization of epithelial stem cells, 2020 – 2023
Grant-in-Aid for Challenging Research (Exploratory) (20K21431). Elucidating the roles of cell surface glycans on epithelial stem cell aging, 2020 – 2021
Grant-in-Aid for Scientific Research for Early-Career Scientists (18K14709), Epithelial stem cells: cellular dynamics and future use in regenerative therapy, 2018 – 2019
Grant-in-Aid for Scientific Research on Innovative Areas “Stem Cell Aging and Disease” (17H05631), Title: Stem cell aging in the skin epidermis: If stem cells divide more, do they age more?, 2017 – 2018
Grant-in-Aid for Scientific Research for Research Activity Start-up (16H06660), Epidermal stem cells: from homeostasis to aging, 2016
Interstellar Initiative/AMED, Elucidating the Cellular and Molecular Mechanisms of Stem Cell Aging, 2020
Nanotech CUPAL (Career-up Allicance)/Nanotech Research Professional (N.R.P.) course, Comprehensive glycome profiling of skin stem cells during aging, 2018 – 2019
Astellas Foundation for Research on Metabolic Disorders/Research grant, Elucidating the roles of cell surface glycans on skin stem cell aging, 2020 - 2021
The Mitsubishi Foundation/Research grant, Elucidating the roles of glycosylation during epidermal stem cell aging, 2020
The Ichiro Kanehara foundation/Research grant, Stem cell dynamics on the ocular surface epithelium, 2019
The Sumitomo foundation/Research grant, Identification of lectin biomarkers to define dynamic glycan alterations during epidermal stem cell aging, 2019
Takeda Science Foundation/Research grant, Bioengineering of stem cell niche, 2018
Naito Foundation/Research grant, Contribution of distinct cell populations during vascular remodeling, 2017 – 2019
Astellas Foundation for Research on Metabolic Disorders/Research grant, Mechanisms of epithelial stem cell aging: implication for future treatments of age-related disorders, 2018
Nakatomi Foundation/Research grant, Identification of lectin biomarkers for aged epidermal stem cells, 2018
Hoyu Science Foundation/Research grant, Identification of lectin biomarkers for aged epidermal stem cells, 2018
Nakajima Foundation/Research grant, Mechanisms of stem cell aging in the skin epidermis, 2017
Uehara Memorial Foundation/Research grant, Stem cell aging in the skin epidermis, 2017
Inamori Foundation/Research grant, Stem cell aging in the skin epidermis, 2017
SENSHIN Medical Research Foundation/Research grant, Elucidating the mechanisms of vascular remodeling: Search for putative stem/progenitor cells residing in adult vessels, 2017
Leave a Nest Co.,ltd. for IKEDARIKA award/Research grant, Stem cell aging in the skin epidermis,
Tsukuba Advanced Research Alliance (TARA Center), University of Tsukuba/The Cooperative Research Project Program of Life Science Center for Survival Dynamics, The roles of ECM protein Fibulin-7 in epidermal stem cell aging, 2020
Gunma University/The joint research program of the Institure for Molecular and Cellular Regulation, Identification of metabolic factors regulating stem cell aging using the African turquoise killifish, 2019
Institute for Frontier Life and Medical Sciences, Kyoto University/Joint Usage/Research Center program, Stem cell dynamics in pregnant skin, 2017, 2019
University of Tsukuba/Basic Research Support Program Type A, Stem cell aging in the skin epidermis, 2016